The organizations receiving support are deeply embedded in the communities they serve and deliver essential services that millions rely on. In the wake of reduced USAID funding, many of these trusted groups—particularly those with limited access to U.S. philanthropic networks—risk being overlooked despite their proven impact. Through PRO’s rigorous project assessment process and GlobalGiving’s grantmaking infrastructure, donors can confidently support organizations delivering measurable, life-changing results.

This funding will help sustain programs that:

  • Expand access to HIV prevention and treatment
  • Provide tuberculosis screenings and treatment referrals
  • Strengthen early identification and treatment of malnutrition
  • Deliver lifesaving care for children
  • Reduce anemia among pregnant and breastfeeding women
  • Improve maternal and child health

“In today’s shifting funding landscape, critical services communities depend upon are at increasingly grave risk,” said Victoria Vrana, CEO of GlobalGiving. “I’m proud that PRO has partnered with us to ensure more than $7 million reaches local organizations, delivering essential care and support where it’s needed most.”

Together, GlobalGiving and PRO are working closely with partners on the ground to maintain essential services, retain skilled staff, and continue reaching people facing urgent health and development challenges.

About Project Resource Optimization (PRO)

Launched in February 2025, PRO is an initiative to identify the most cost-effective life saving projects that were previously operated through USAID funding prior to its dismantling in an effort to enable private philanthropy to preserve the most important health and humanitarian programming that would otherwise be lost. The PRO database and approach are public goods that donors can use to inform their own funding decisions. Led by economists and cost-effectiveness experts with experience leading humanitarian and development organizations, PRO identifies lists of critical funding opportunities. By asking targeted questions of top experts in the fields of health and humanitarian foreign aid, PRO’s transparent assessment is intended to support donors looking to help get impact back on track, fast. To learn more, visit proimpact.tools.